eggNOG 5.0 now available

Discover EggNOG 4.5.1
A database of orthologous groups and functional annotation
  • Organisms
    2,031
  • Viruses
    352
  • Orthologous Groups
    190k
  • Trees & Algs.
    1.9M

What's new in version 4.5.1 (Nov 2016)

  • Added new tool eggNOG-mapper for fast functional annotations of sequence collections
  • Minor improvements in phylogenetic tree visualization (e.g. Show original sequence names)

What's new in version 4.5 (May 2015)

  • OG building updated: Clusters of Orthologous Groups are now hierarchically consistent across taxonomic levels.
  • Sequence search is now based on a faster HMMER implementation.
  • A new data channel labeled fine-grained orthologs provides pairwise orthology predictions based on the analysis of phylogenetic trees.
  • Added Gene ontology terms and KEGG pathways. Relative frequency of GOs and pathways are reported per group.
  • HMM models are available for all Orthologous Group.
  • Taxonomic level adjustment is performed transparently when target taxa is added to the query, thus ensuring more accurate results.
  • NOG names are now unique, thus avoiding collisions among versions
  • Programmatic queries are now possible using the eggnog RESTful web API
  • A number of new features have been added to the web interface: Fast ID searching, inline visualization of trees, alignments and taxonomic profiles. Gene Ontology and protein domain frequencies. Orthology predictions grouped by species and automatically adjusted to queries, and more!

Citation

eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences. Jaime Huerta-Cepas, Damian Szklarczyk, Kristoffer Forslund, Helen Cook, Davide Heller, Mathias C. Walter, Thomas Rattei, Daniel R. Mende, Shinichi Sunagawa, Michael Kuhn, Lars Juhl Jensen, Christian von Mering, and Peer Bork.
Nucl. Acids Res. (04 January 2016) 44 (D1): D286-D293. doi: 10.1093/nar/gkv1248

Previous versions

Contact information
  • huerta@embl.de
    damian.szk@gmail.com
    forslund@embl.de
  • bork@embl.de
    mering@imls.uzh.ch
    lars.juhl.jensen@cpr.ku.dk
  • ...
    Jaime Huerta-Cepas
    Damian Szklarczyk
    Kristoffer Forslund
    Helen Cook
    Davide Heller
    Mathias Walter
    Thomas Rattei
    Daniel Mende
    Shinichi Sunawawa
    Michael Kuhn
    Lars J. Jensen
    Christian von Mering
    Peer Bork
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